Product Description

INT2 Polyclonal Antibody

Catalogue Numbers: BS62395-50, BS62395-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Swiss-Prot: Q9H0H0

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB, IHC

All Applications: WB:1:500~1:1000 IHC:1:50~1:200

Background: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.

Purification and Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: INT2 polyclonal antibody detects endogenous levels of INT2 protein.

Extra Notes: Western blot (WB) analysis of INT2 polyclonal antibody at 1:500 dilution
LaneA:HepG2 whole cell lysate
LaneB:HCT116 whole cell lysate
LaneC:Hela whole cell lysate
LaneD:PC12 whole cell lysate
LaneE:CT-26 whole cell lysate

Bioworld Molecular Weight: ~ 134 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Integrator complex subunit 2; Int2; INTS2; KIAA1287

Immunogen: Synthetic peptide, corresponding to Human INT2.

Conjugate: Unconjugated

Modification: Unmodified