Integrin α6 rabbit pAb - ES4320

Integrin α6 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4320-50, ES4320-100

Citations, Manuals and MSDS Available upon request.

Background: integrin subunit alpha 6 (ITGA6) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Alternate Name: ITGA6; Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD49f

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ITGA6. AA range:901-950

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 125kD

Human Gene ID: 3655

Human SWISS Prot NO: P23229

Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor.

Research Use Only