Product Description

Integrin alpha V Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10296-50, MB10296-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P06756

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 116 kDa; Observed MW: 135 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Integrin alpha V in C6, 3T3, Hela lysates using Integrin alpha V antibody., Immunohistochemistry analysis of paraffin-embedded Human tonsil using Integrin alpha V antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: ITGAV; MSK8; VNRA; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51

Immunogen: Recombinant protein of human Integrin alpha V

Conjugate: Unconjugated

Modification: Unmodified