Integrin beta 3 Polyclonal Antibody-BZ16468

Integrin beta 3 Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16468-50, BZ16468-100

Swiss-Prot: P05106

Host: Rabbit

Integrin beta 3 Polyclonal Antibody-BZ16468

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human

Applications: WB, IHC-P, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background: Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity).

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 87 kDa; Observed MW: 87 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Integrin beta 3 in 3T3Lysates using Integrin beta 3 antibody., Western blot analysis of Integrin beta 3 in NIH3T3Lysates using Integrin beta3 antibody.

Alternative Name: ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human ITGB3. AA range:621-670

Modification: Unmodified

Conjugate: Unconjugated