Product Description

Integrin beta 4 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BZ17003-50, BZ17003-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regμlation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC-P

Alternate Names: CD104

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Recombinant protein of mouse Integrin beta 4

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 202 kDa, Observed MW: 202 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: A2A863

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Research Use Only