INTS2 Polyclonal Antibody-BS60745

INTS2 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS60745-50, BS60745-100

Sizes: 50µl, 100µl

Swiss-Prot: Q9H0H0

Host: Rabbit

Reactivity: Human

Applications: IHC

Background: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267).

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: INTS2 polyclonal antibody detects endogenous levels of INTS2 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of INTS2 polyclonal antibody in paraffin-embedded human liver cancer tissue at 1:50.

Bioworld Molecular Weight: ~ 134 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Integrator complex subunit 2; Int2; INTS2; KIAA1287

Immunogen: Synthetic peptide, corresponding to amino acids 50-100 of Human INTS2.

Conjugate: Unconjugated

Modification: Unmodified