IP3 Receptor Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90732-50, BS90732-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q14643(Human) P11881(Mouse) P29994(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC FC
All Applications: WB:1:500-1:1,000
IHC:1:50-1:200
FC:1:50-1:100
Background: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.
Purification and Purity: Peptide affinity purified.
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: IP3 Receptor polyclonal antibody detects endogenous levels of IP3 Receptor protein.
Bioworld Molecular Weight: 314 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of IP3 Receptor on Hela cell lysate using anti-IP3 Receptor antibody at 1/500 dilution., Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.
Alternative Name: IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1, 4, 5-trisphosphate receptor, 5-trisphosphate receptor type 1, DKFZp313E1334, DKFZp313N1434, inositol 1 4 5 triphosphate receptor type 1, Inositol 1 4 5 trisphosphate Receptor Type 1, Inositol 1, InsP3R1, IP3, IP3 receptor, IP3 receptor isoform 1, IP3R 1, IP3R, IP3R1, ITPR 1, Itpr1, ITPR1, SCA15, SCA16, SCA29, Type 1 inositol 1 4 5 trisphosphate receptor, Type 1 inositol 1, Type 1 InsP3 receptor,
Immunogen: Synthetic peptide within C-terminal human IP3 Receptor.
Conjugate: Unconjugated
Modification: Unmodified