Product Description

IP3 Receptor Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90733-50, BS90733-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q14643(Human) P11881(Mouse) P29994(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB:1:500
IHC:1:50-1:200

Background: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded mouse hippocampus tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.

Bioworld Molecular Weight: 314 kDa

Specificity: IP3 Receptor polyclonal antibody detects endogenous levels of IP3 Receptor protein.

Alternative Name: IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1, 4, 5-trisphosphate receptor, 5-trisphosphate receptor type 1, DKFZp313E1334, DKFZp313N1434, inositol 1 4 5 triphosphate receptor type 1, Inositol 1 4 5 trisphosphate Receptor Type 1, Inositol 1, InsP3R1, IP3, IP3 receptor, IP3 receptor isoform 1, IP3R 1, IP3R, IP3R1, ITPR 1, Itpr1, ITPR1, SCA15, SCA16, SCA29, Type 1 inositol 1 4 5 trisphosphate receptor, Type 1 inositol 1, Type 1 InsP3 receptor,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified