IP3R-I (phospho Ser1598) rabbit pAb - ES5964

IP3R-I (phospho Ser1598) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5964-50, ES5964-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an intracellular receptor for inositol 1, 4, 5-trisphosphate. Upon stimulation by inositol 1, 4, 5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009],

Alternate Name: ITPR1; INSP3R1; Inositol 1; 4, 5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; InsP3R1; Type 1 inositol 1, 4, 5-trisphosphate receptor; Type 1 InsP3 receptor

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Inositol 1, 4, 5-trisphosphate R1 around the phosphorylation site of Ser1598/1588. AA range:1566-1615

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 3708

Human SWISS Prot NO: Q14643

Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Endoplasmic reticulum and secretory granules (By similarity).

Research Use Only