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IPO8 Polyclonal Antibody - E-AB-16522

IPO8 Polyclonal Antibody - E-AB-16522

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IPO8 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16522-60, E-AB-16522-120, E-AB-16522-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: IPO8

Target Synonym: FLJ26580; Imp 8; Imp8; Importin-8; Importin8; IPO 8; IPO8; IPO8; Ran binding protein 8; RAN BP8; Ran-binding protein 8; RANBP 8; RanBP8

Research Areas: Epigenetics and Nuclear Signaling, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O15397

Background: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Concentration: 1.2 mg/mL

Immunogen: Synthetic peptide of human IPO8

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:100-1:300

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only