IQGAP1 rabbit pAb - ES2639

IQGAP1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2639-50, ES2639-100

Citations, Manuals and MSDS Available upon request.

Background: IQ motif containing GTPase activating protein 1 (IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],

Alternate Name: IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human IQGAP1. AA range:247-296

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 190kD

Human Gene ID: 8826

Human SWISS Prot NO: P46940

Subcellular Location: Cell membrane. Nucleus. Cytoplasm. Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816).

Research Use Only