IRAK-4 Monoclonal Antibody - BT-MCA0786

IRAK-4 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0786-50, BT-MCA0786-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Signal transduction; Immunology; Cardiovascular

Target Protein: IRAK4

Applications: WB, IHC-p, IF, FCM, ELISA

Reactivity: Human,Mouse,Monkey

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Interleukin-1 receptor-associated kinase 4

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q8TDF7

GeneID: Human: 51135

Research Use Only