IRAK-M rabbit pAb - ES4616

IRAK-M rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4616-50, ES4616-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],

Alternate Name: IRAK3; Interleukin-1 receptor-associated kinase 3; IRAK-3; IL-1 receptor-associated kinase M; IRAK-M

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human IRAK3. AA range:491-540

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 68kD

Human Gene ID: 11213

Human SWISS Prot NO: Q9Y616

Subcellular Location: Cytoplasm. Nucleus. In dendritic cells, translocates into the nucleus upon IL33 stimulation.

Research Use Only