Product Description

IRAK4 Polyclonal Antibody

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS78260-50, BS78260-100

Swiss-Prot: Q9NWZ3

Host: Rabbit

IRAK4 Polyclonal Antibody-BS78260

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IF/ICC

All Applications: WB,1:500 - 1:2000 | IF/ICC,1:50 - 1:200

Background: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Unmodification

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunofluorescence analysis of RAW264.7 cells using IRAK4 Rabbit pAb at dilution of 1:50. Blue: DAPI for nuclear staining., Immunofluorescence analysis of THP-1 cells using IRAK4 Rabbit pAb at dilution of 1:50. Blue: DAPI for nuclear staining.

Alternative Name: IRAK4; IPD1; IRAK-4; NY-REN-64; REN64; interleukin-1 receptor-associated kinase 4

Immunogen: Recombinant fusion protein of human IRAK4(NP_057207.2).

Modification: Unmodified

Conjugate: Unconjugated