IRF5 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90739-50, BS90739-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q13568(Human)
Host: Rabbit
Reactivity: Human
Applications: WB, IHC FC
All Applications: WB:1:1,000-1:5,000
FC:1:50-1:100
IHC:1:50-1:200
Background: Interferon regulatory factor 5 (IRF-5), belongs to the IRF family of DNA-binding factors, which includes IRF-1, IRF-2, IRF-3, IRF-4, IRF-6, IRF-7, ISGF-3γ p48 and IFN consensus sequence-binding protein (ICSBP). The IRF family regulate both interferon and interferon-inducible genes. IRF-5, like IRF-3 and IRF-7, is a direct transducer of virus-mediated signaling and plays a role in the expression of multiple cytokines/chemokines. Although IRF-5 is a direct target of p53, its cell cycle regulatory and proapoptotic effects are p53 independent.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: IRF5 polyclonal antibody detects endogenous levels of IRF5 protein.
Bioworld Molecular Weight: 56 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of IRF5 on THP-1 cells lysates using anti-IRF5 antibody at 1/1,000 dilution., Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-IRF5 antibody. Counter stained with hematoxylin.
Alternative Name: IRF-5, IRF5, Interferon regulatory factor 5, Interferon regulatory factor 5 bone marrow variant, IRF 5, IRF-5, Irf5, IRF5, SLEB10,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified