IRGM Polyclonal Antibody - BT-AP10497

IRGM Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10497-20, BT-AP10497-50, BT-AP10497-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohnandapos;s disease and tuberculosis.

Research Areas: Cancer; Cardiovascular; Immunology; Metabolism; Stem cells

Target Protein: IRGM

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Immunity-related GTPase family M protein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: A1A4Y4; Rat: Q6AYC2

Synonyms: Immunity-related GTPase family M protein;EC 3.6.5.-;Immunity-related GTPase family M protein 1;Interferon-inducible protein 1;LPS-stimulated RAW 264.7 macrophage protein 47 homolog;LRG-47

GeneID: Human: 345611

Research Use Only