IRS2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A7945-20, A7945-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 137kDa
Observed Molecular Weight: 180kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 8660
SWISS: Q9Y4H2
Alternate Names: IRS-2; IRS2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Growth factors, Endocrine Metabolism, Insulin Receptor Signaling Pathway, Endocrine and metabolic diseases, Diabetes, Immunology Inflammation, Cardiovascular, Heart, Cardiovascular diseases, Heart disease.
NCBI Alias: IRS2
Research Use Only