ISCU Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS71895-50, BS71895-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9H1K1
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB 1:500 - 1:2000
Background: This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ISCU polyclonal antibody detects endogenous levels of ISCU protein.
Bioworld Molecular Weight: 18kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western Blot analysis of extracts of various cell lines, using ISCU Antibody at 1:1000 dilution.
Alternative Name: 2310020H20Rik; HML; ISU2; NIFU; NIFUN; hnifU
Immunogen: Recombinant protein of human ISCU
Conjugate: Unconjugated
Modification: Unmodified