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Islet 1 Polyclonal Antibody-BZ16939

Islet 1 Polyclonal Antibody-BZ16939

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Islet 1 Polyclonal Antibody

Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16939-50, BZ16939-100

Swiss-Prot: P61371

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, ICC/IF, IP, FC

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background: ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Calculated MW: 39 kDa; Observed MW: 39 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Islet1 in HeLa lysates using Islet 1 antibody.

Alternative Name: ISL1; Insulin gene enhancer protein ISL-1; Islet-1

Immunogen: A synthesized peptide derived from human Islet1

Conjugate: Unconjugated

Modification: Unmodified