Product Description

Islet 1 Polyclonal Antibody

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Sizes: 50µl, 100µl

Catalogue Numbers: BZ17031-50, BZ17031-100

Swiss-Prot: P61371

Host: Rabbit

Islet 1 Polyclonal Antibody-BZ17031

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human

Applications: WB, ICC/IF, FC, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background: ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 39 kDa; Observed MW: 39 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of Islet 1 in SH-SY5Y using Islet 1 antibody,and DAPI., Western blot analysis of Islet 1 in Jurkat, K562Lysates using Islet 1 antibody.

Alternative Name: ISL1; Insulin gene enhancer protein ISL-1; Islet-1

Immunogen: A synthetic peptide of human Islet 1

Modification: Unmodified

Conjugate: Unconjugated