ITBP2 Polyclonal Antibody - BT-AP10535

ITBP2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10535-20, BT-AP10535-50, BT-AP10535-100

Citations, Manuals and MSDS Available upon request.

Background: The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms. The presence of Ca(2+) ions does not prevent binding of a fragment consisting of the second cysteine rich repeat and the tail domain but prevents the binding of the full-length protein.,May play a role during maturation and/or organization of muscles cells.,Contains 1 CS domain.,Contains 2 CHORD domains.,subunit:Interacts with beta-1 integrin subunit. This interaction is regulated by divalent cations, and it occurs only in absence of calcium.,tissue specificity:Expressed in skeletal and cardiac muscles but not in other tissues.,

Research Areas: Cardiovascular; Signal transduction

Target Protein: ITGB1BP2

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Integrin beta-1-binding protein 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9UKP3; Mouse: Q9R000

Synonyms: Integrin beta-1-binding protein 2;Melusin

GeneID: Human: 26548

Research Use Only