ITGA3 (heavy chain, Cleaved-Phe33) rabbit pAb - ES20005

ITGA3 (heavy chain, Cleaved-Phe33) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20005-50, ES20005-100

Citations, Manuals and MSDS Available upon request.

Background: integrin subunit alpha 3 (ITGA3) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015],

Alternate Name: Integrin alpha-3 (CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3; VLA-3 subunit alpha; CD antigen CD49c) [Cleaved into: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain]

Source: Rabbit

Applications: WB; IF; ELISA; IHC

Dilution: WB 1:500-2000; IF/ICC 1:50-200; ELISA 1:2000-20000; IHC-p 1:50-200

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human ITGA3 (heavy chain, Cleaved-Phe33)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 93 115kD

Human Gene ID: 3675

Human SWISS Prot NO: P26006

Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. Cell projection, invadopodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. Enriched preferentially at invadopodia, cell membrane protrusions that correspond to sites of cell invasion, in a collagen-dependent manner.

Research Use Only