ITGA8 Polyclonal Antibody
Catalogue Numbers: BS60756-50, BS60756-100
Sizes: 50µl, 100µl
Alternative Name: Integrin alpha-8; ITGA8
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P53708
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: Integrins are heterodimers composed of noncovalently associated transmembrane å and ∫ subunits. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. Integrin å8 is expressed in contractile interstitial cells and smooth muscle cells and is upregulated in lung injury. Integrin å8 is also a marker for smooth muscle cells, expressed as early as alpha smooth muscle actin. The Integrin å8 chain is expressed in the glomerulus exclusively by mesangial cells and may play an important role for maintaining tissue integrity in the glomerulus during glomerular injury.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ITGA8 polyclonal antibody detects endogenous levels of ITGA8 protein.
Bioworld Molecular Weight: ~ 117 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of ITGA8 polyclonal antibody at 1:500 dilution
Lane 1: Hela whole cell lysate
Lane 2: Raw264.7 whole cell lysate
Lane 3: PC12 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human ITGA8.
Conjugate: Unconjugated
Modification: Unmodified