ITGAM Monoclonal Antibody - BT-MCA4731

ITGAM Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4731-50, BT-MCA4731-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Signal transduction, Stem cells, Neuroscience, Tags and cell markers, Immunology

Target Protein: ITGAM

Applications: IHC, FCM

Clonality: Monoclonal

Clone ID: 3A4B10

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: ITGAM

Immunogen: Purified recombinant fragment of human ITGAM (AA: 623-728) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 127.1kDa

UniProt Accession: P11215

Synonyms: CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6

GeneID: 3684

Research Use Only