Product Description

ITGAV (light chain, Cleaved-Asp891) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26511-50, RA26511-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: integrin subunit alpha V (ITGAV) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Integrin alpha-V (Vitronectin receptor subunit alpha;CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain, Integrin alpha-V light chain]

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight: 17 110

Protein Molecular Weight (kDa): 17 110

Storage: -20°C/1 year

Human Gene ID: 3685

Human SwissProt Number: P06756

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only