Product Description

ITPR1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61363-50, BS61363-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Inositol 1, 4, 5-triphosphate (IP3) functions as a second messenger for a myriad of extracellμlar stimμli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellμlar levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4, 5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1, 4, 5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Inositol 1, 4, 5-trisphosphate receptor type 1, IP3 receptor isoform 1, IP3R 1, InsP3R1, Type 1 inositol 1, 4, 5-trisphosphate receptor, Type 1 InsP3 receptor, ITPR1, INSP3R1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding Human ITPR1.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: ITPR1 Polyclonal Antibody detects endogenous levels of ITPR1 protein.

Molecular Weight: ~ 320 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q14643

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only