IVNS1ABP Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-67617-60, E-AB-67617-120, E-AB-67617-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: IVNS1ABP
Target Synonym: IVNS1ABP; FLARA3; HSPC068; KLHL39; ND1; NS-1; NS1-BP; NS1BP
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9Y6Y0
Background: Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (By similarity. Protects cells from cell death induced by actin destabilization (By similarity. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. In addition, functions as a negative regulator of BCR(KLHL20 E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors. Inhibits pre-mRNA splicing (in vitro.
Concentration: 1 mg/mL
Immunogen: Recombinant fusion protein of human IVNS1ABP
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 71kDa
Observed MW: 72kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only