IYD Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-92942-60, E-AB-92942-120, E-AB-92942-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: IYD
Target Synonym: IYD; C6orf71; DEHAL1; IYD-1; TDH4
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Mouse
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q6PHW0
Background: This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human IYD
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:200-1:2000
Calculated MW: 22kDa/28kDa/31kDa/32kDa/33kDa
Observed MW: 25kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only