Jagged1 rabbit pAb - ES4131

Jagged1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4131-50, ES4131-100

Citations, Manuals and MSDS Available upon request.

Background: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008],

Alternate Name: JAG1; JAGL1; Protein jagged-1; Jagged1; hJ1; CD339

Source: Rabbit

Applications: IF; WB; IHC; ELISA

Dilution: IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human JAG1. AA range:981-1030

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 140kD

Human Gene ID: 182

Human SWISS Prot NO: P78504

Subcellular Location: Membrane; Single-pass type I membrane protein.

Research Use Only