JAK1 mouse Monoclonal Antibody (7G6) - BT-MCA0794

JAK1 mouse Monoclonal Antibody (7G6)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0794-20, BT-MCA0794-50, BT-MCA0794-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.

Research Areas: Signal transduction; Cancer; Epigenetics and nuclear signaling; Cell biology

Target Protein: JAK1

Applications: IHC-p, IF

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: JAK1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P23458; Mouse: P52332

Synonyms: JAK1

GeneID: Human: 3716

Research Use Only