JAK3 Monoclonal Antibody - BT-MCA4724

JAK3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4724-50, BT-MCA4724-100

Citations, Manuals and MSDS Available upon request.

Background: JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Research Areas: Signal Transduction

Target Protein: JAK3

Applications: WB, ICC, FCM

Reactivity: Human, Mouse

Clonality: Monoclonal

Clone ID: 5H2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: JAK3

Immunogen: Purified recombinant fragment of human JAK3 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 125kDa

UniProt Accession: P52333

Synonyms: JAKL, LJAK

GeneID: 3718

Research Use Only