JAK3 (phospho Tyr785) rabbit pAb - ES5975

JAK3 (phospho Tyr785) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5975-50, ES5975-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],

Alternate Name: JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human JAK3 around the phosphorylation site of Tyr785. AA range:751-800

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 125kD

Human Gene ID: 3718

Human SWISS Prot NO: P52333

Subcellular Location: Endomembrane system; Peripheral membrane protein. Cytoplasm.

Research Use Only