JAML1 rabbit pAb - ES10721

JAML1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES10721-50, ES10721-100

Citations, Manuals and MSDS Available upon request.

Background: domain:The Ig-like V-type domain 2 mediates interaction with CXADR., function:May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells., induction:Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells., similarity:Belongs to the immunoglobulin superfamily., similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains., subcellular location:Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN., subunit:Interacts with CXADR., tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 43kD

Human Gene ID: 120425

Human SWISS Prot NO: Q86YT9

Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cell junction. Localized at the plasma membrane and enriched in areas of cell-cell contacts (PubMed:12869515).

Research Use Only