JMJD6 (N-terminus) Monoclonal Antibody-MB0100

JMJD6 (N-terminus) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB0100-50, MB0100-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q6NYC1

Host: Mouse

Reactivity: Human

Applications: WB, ICC

All Applications: WB: 1:1000
ICC: 1:100~200

Background: Cells undergoing apoptosis lose the asymmetry of plasma membrane phospholipids, and phosphatidylserine is exposed on the outer surface of the membrane. The phosphatidylserine receptor (PSR) specifically recognizes phosphatidylserine and this binding triggers the phagocytosis of apoptotic cells by either macrophages or dendritic cells. PSR is expressed on the surface of macrophages, fibroblasts, and epithelial cells, and it has been detected in high levels in heart, skeletal muscle, and kidney tissues and is extensively glycosylated. The mammalian phosphatidylserine receptor displays significant homology to Caenorhabditis elegans and Drosophila melanogaster proteins, which suggests that PSR has been conserved throughout phylogeny.

Purification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of JMJD6 and does not cross-react with related proteins

Bioworld Molecular Weight: Predicted band size: 46KDa
Observed band size: 62KDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot detection of JMJD6 (N-terminus) antibody in Hela and HL-60 lysates using JMJD6 (N-terminus) antibody (1:1000 diluted)., Immunocytochemistry of HeLa cells using anti- JMJD6(N-terminus) antibody diluted 1:200

Alternative Name: PSR; PTDSR; PTDSR1; KIAA0585; jumonji domain containing 6; Lysyl-hydroxylase JMJD6; Phosphatidylserine receptor; PTDSR; KIAA0585; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; PSR; Peptide-lysine 5-dioxygenase JMJD6; Protein PTDSR

Immunogen: Synthetic peptide, corresponding to the N-terminus of Human JMJD6.

Conjugate: Unconjugated

Modification: Unmodified