Product Description

JMY Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26558-50, RA26558-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage., induction:By E2F., PTM:Ubiquitinated by MDM2, leading to its subsequent degradation by the proteasome. In case of DNA damage, the interaction with MDM2 is altered, preventing degradation and allowing interaction with p300/EP300 and its function in p53/TP53 stress response., similarity:Contains 1 WH2 domain., subunit:Interacts with p300/EP300, the complex being recruited to activated p53/TP53. Interacts with TTC5.,

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: JMY, Junction-mediating and -regulatory protein

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight: 130

Protein Molecular Weight (kDa): 130

Storage: -20°C/1 year

Human Gene ID: 133746

Human SwissProt Number: Q8N9B5

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only