Product Description

JMY Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26558-50, RA26558-100

Citations, Manuals and MSDS Available upon request.

Background: function:Cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage.,induction:By E2F.,PTM:Ubiquitinated by MDM2, leading to its subsequent degradation by the proteasome. In case of DNA damage, the interaction with MDM2 is altered, preventing degradation and allowing interaction with p300/EP300 and its function in p53/TP53 stress response.,similarity:Contains 1 WH2 domain.,subunit:Interacts with p300/EP300, the complex being recruited to activated p53/TP53. Interacts with TTC5.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: JMY; Junction-mediating and -regulatory protein

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 133746

Protein MW (KDa): 130

SWISS: Q8N9B5

Source: Rabbit

Research Use Only