JNK1 Mouse Monoclonal Antibody - RA11555

JNK1 Mouse Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11555-50, RA11555-100

Citations, Manuals and MSDS Available upon request.

Background: mitogen-activated protein kinase 8 (MAPK8) Homo sapiens The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spl

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB; IF/ICC

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5599

Protein MW (KDa): 46,54

SWISS: P45983

Source: Mouse

Research Use Only