JNK3 Monoclonal Antibody - RA11557

JNK3 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11557-50, RA11557-100

Citations, Manuals and MSDS Available upon request.

Background: mitogen-activated protein kinase 10 (MAPK10) Homo sapiens The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2015],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 5602

SWISS: P53779

Source: Mouse

Research Use Only