Junctional Adhesion Molecule 1 Monoclonal Antibody-MB12089

Junctional Adhesion Molecule 1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12089-50, MB12089-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9Y624

Host: Rabbit

Reactivity: Human

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 33 kDa; Observed MW: 33 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Junctional Adhesion Molecule 1/JAMA in Hela, A549 lysates using Junctional Adhesion Molecule 1 antibody., Immunocytochemistry analysis of Junctional Adhesion Molecule 1/JAMA in MCF-7 using Junctional Adhesion Molecule 1/JAMA antibody, and DAPI

Alternative Name: F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321

Immunogen: Recombinant protein of human Junctional Adhesion Molecule 1/JAM-A

Conjugate: Unconjugated

Modification: Unmodified