Product Description

Junctional Adhesion Molecule 1 Polyclonal Antibody

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16663-50, BZ16663-100

Swiss-Prot: Q9Y624

Host: Rabbit

Junctional Adhesion Molecule 1 Polyclonal Antibody-BZ16663

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 33 kDa; Observed MW: 33 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of JAM1 in HeLaLysates using Junctional Adhesion Molecule 1 antibody., Immunohistochemistry analysis of paraffin-embedded Human blader cancer using JAM1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321

Immunogen: A synthesized peptide derived from human JAM1

Modification: Unmodified

Conjugate: Unconjugated