Product Description

K2P4.1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90757-50, BS90757-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9NYG8(Human)

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC FC

All Applications: WB:1:500
IHC:1:50-1:200
FC:1:50-1:100

Background: Voltage-insensitive potassium channel (PubMed:22282805). Channel opening is triggered by mechanical forces that deform the membrane (PubMed:22282805, PubMed:25471887, PubMed:25500157). Channel opening is triggered by raising the intracellular pH to basic levels (By similarity). The channel is inactive at 24 degrees Celsius (in vitro); raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius (By similarity). Plays a role in the perception of pain caused by heat (By similarity). Plays a role in the sensory perception of pain caused by pressure (By similarity).

Purification and Purity: Peptide affinity purified.

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: K2P4.1 polyclonal antibody detects endogenous levels of K2P4.1 protein.

Bioworld Molecular Weight: 43 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of K2P4.1 on different lysates using anti-K2P4.1 antibody at 1/500 dilution.
Positive control:
Lane 1: Mouse colon
Lane 2: Rat kidney, Immunohistochemical analysis of paraffin-embedded rat large intestine tissue using anti-K2P4.1 antibody. Counter stained with hematoxylin.

Alternative Name: TRAAK, Two pore K(+) channel KT4.1, KCNK4, TRAAK, K2p4.1, K2P4.1 potassium channel, KCNK 4, MGC144821, Potassium channel subfamily K member 4, Potassium inwardly rectifying channel subfamily K member 4, TRAAK, TRAAK1, TRAAKt, TWIK related arachidonic acid stimulated potassium channel protein, Two pore K(+) channel KT4.1, Two pore K+ channel KT4.1, Two pore potassium channel KT4.1,

Immunogen: Synthetic peptide within human K2P4.1 aa 320-380.

Conjugate: Unconjugated

Modification: Unmodified