Kallikrein 3 Monoclonal Antibody-MB66641

Kallikrein 3 Monoclonal Antibody

Catalogue Numbers: MB66641-50, MB66641-100

Sizes: 50µl, 100µl

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P07288

Host: Mouse

Reactivity: Human

Applications: WB, FC

All Applications: WB (1/500 - 1/1000), FC (1/50 - 1/100)

Background: Kallikrein 3 (KLK3), also known as Prostate Specific Antigen (PSA), is a member of the glandular kallikrein subfamily of serine proteases. It is produced by prostate epithelial cells and is secreted into prostatic ducts. Upon cleavage of 7 amino-terminal amino acids, it is activated to liquefy semen in the seminal coagulum. Although PSA/KLK3 is produced in healthy individuals, investigators have found abnormally high levels in the blood of men with advanced prostate cancer.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of Kallikrein 3 protein.

Extra Notes: Western blot analysis of Kallikrein 3 expression in human KLK3 recombinant protein (A) whole cell lysates.

Bioworld Molecular Weight: ~ 34 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: APS; Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase

Immunogen: Purified recombinant fragment of human KLK3 expressed in E. Coli.

Conjugate: Unconjugated

Modification: Unmodified