Product Description

Kanadaptin Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP04732-20, BT-AP04732-50, BT-AP04732-100

Citations, Manuals and MSDS Available upon request.

Background: An important paralog of SLC4A1AP is PPP1R8. Kanadaptin (kidney anion exchanger adaptor protein) is a widely expressed protein, shown previously to interact with the cytosolic domain of mouse Cl-/HCO3- anion exchanger 1 (kAE1) but not erythroid AE1 (eAE1) by a yeast-two hybrid assay. Kanadaptin was co-localized with kAE1 in intracellular membranes but not at the plasma membrane in alpha-intercalated cells of rabbit kidney. It was suggested that kanadaptin is an adaptor protein or chaperone involved in targeting kAE1 to the plasma membrane.

Research Areas: Cardiovascular

Target Protein: SLC4A1AP

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Kanadaptin Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 88814

UniProt Accession: Human: Q9BWU0

Synonyms: SLC4A1AP; HLC3; Kanadaptin; Human lung cancer oncogene 3 protein; HLC-3; Kidney anion exchanger adapter protein; Solute carrier family 4 anion exchanger member 1 adapter protein

GeneID: Human: 22950

Research Use Only