Product Description

KAT6A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10618-20, BT-AP10618-50, BT-AP10618-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with autosomal dominant mental retardation-32. Alternative splicing results in multiple transcript variants.

Research Areas: Epigenetics and nuclear signaling

Target Protein: KAT6A

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Histone acetyltransferase KAT6A

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q92794; Mouse: Q8BZ21; Rat: Q5TKR9

Synonyms: Histone acetyltransferase KAT6A;EC 2.3.1.48;MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3;MYST-3;Monocytic leukemia zinc finger protein;Runt-related transcription factor-binding protein 2;Zinc f

GeneID: Human: 7994

Research Use Only