KAT7 Monoclonal Antibody-MB12090

KAT7 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12090-50, MB12090-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O95251

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 71 kDa; Observed MW: 71 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of KAT7 in HCT116 using KAT7 antibody, and DAPI., Western blot analysis of KAT7/Hbo1/MYST2 in Hela, A549, MCF-7, 293T lysates using KAT7/Hbo1/MYST2 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using KAT7/Hbo1/MYST2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: HBO1; HBOA; MYST2; ZC2HC7

Immunogen: Recombinant protein of human KAT7/Hbo1/MYST2

Conjugate: Unconjugated

Modification: Unmodified