KBTBD8 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-92076-60, E-AB-92076-120, E-AB-92076-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: KBTBD8
Target Synonym: TA-KRP; TAKRP; KBTBD8
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Mouse, Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q8NFY9
Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1 E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8 complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human KBTBD8
Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Observed MW: 69kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only