KCMB3 Polyclonal Antibody - BT-AP10629

KCMB3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10629-20, BT-AP10629-50, BT-AP10629-100

Citations, Manuals and MSDS Available upon request.

Background: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.

Research Areas: Neuroscience; Signal transduction

Target Protein: KCNMB3

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Calcium-activated potassium channel subunit beta-3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9NPA1; Rat: A7VL23

Synonyms: Calcium-activated potassium channel subunit beta-3;BK channel subunit beta-3;BKbeta3;Hbeta3;Calcium-activated potassium channel, subfamily M subunit beta-3;Charybdotoxin receptor subunit beta

GeneID: Human: 27094

Research Use Only