Product Description

KCNA1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS76995-50, BS76995-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q09470

Host: Rabbit

Reactivity: Mouse, Rat

Applications: IF/ICC

All Applications: IF/ICC,1:50 - 1:200

Background: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Unmodification

Extra Notes: Immunofluorescence analysis of mouse brain using KCNA1 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: KCNA1; AEMK; EA1; HBK1; HUK1; KV1.1; MBK1; MK1; RBK1

Immunogen: Recombinant fusion protein of human KCNA1(NP_000208.2).

Conjugate: Unconjugated

Modification: Unmodified