Product Description

KCNAB1/Kv beta 1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65438-50, BS65438-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellμlar distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming å subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV∫, also known as KCNAB1 (potassium voltage-gated channel, shaker-related subfamily, beta member 1), is a 419 amino acid accessory K+ channel protein that exists as three alternatively spliced isoforms and regμlates the activity of the pore-forming å subunit. It is expressed in brain, with highest levels detected in caudate nucleus, hippocampus and thalamus.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep

Host: Rabbit

Applications: WB

Alternate Names: hKvb3, hKvBeta3, K(+) channel subunit beta-1, KCAB1_HUMAN, KCNA1B, KCNAB1, KV-BETA-1, Kvb1.3, Voltage-gated potassium channel beta-1 subunit, Voltage-gated potassium channel subunit beta-1.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human KCNAB1/Kv beta 1:131-230/419

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: KCNAB1/Kv beta 1 Polyclonal Antibody detects endogenous levels of KCNAB1/Kv beta 1 protein.

Molecular Weight: 47 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q14722

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only