KCNE1L Polyclonal Antibody
Catalogue Numbers: BS60501-50, BS60501-100
Sizes: 50µl, 100µl
Alternative Name: Potassium voltage-gated channel subfamily E; member 1-like protein; AMME syndrome candidate gene 2 protein; KCNE1L; AMMECR2; Organismi Homo sapiens (Human)
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9UJ90
Host: Rabbit
Reactivity: Human
Applications: WB
All Applications: WB: 1:500~1:1000
Background: KCNE genes encode small, single transmembrane domain peptides that associate with pore-forming å-subunits to form K+ channels with unique characteristics. Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. KCNE1L (KCNE1-like), also known as KCNE5, potassium voltage-gated channel subfamily E member 1-like protein or AMMECR2, is a 142 amino acid single-pass type I membrane protein belonging to the potassium channel KCNE family. Defects of the KCNE1L gene have been linked to the cardiac and some neurological abnormalities observed in patients with AMME (Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis) contiguous gene syndrome. KCNE1L is primarily expressed in skeletal muscle, brain, placenta, spinal cord and heart.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: KCNE1L polyclonal antibody detects endogenous levels of KCNE1L protein.
Bioworld Molecular Weight: ~ 15 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of KCNE1L polyclonal antibody at 1:500 dilution
Lane 1: Hela whole cell lysate
Lane 2: MCF-7 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human KCNE1L.
Conjugate: Unconjugated
Modification: Unmodified