Product Description

KCNN3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS7920-50, BS7920-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Small-conductance, calcium-activated K+ channels (SK channels) are activated in a voltage-independent manner, and they have a small unit conductance and high sensitivity to calcium. SK channels 1-3 contain intracellμlar N- and C- termini and 6 conserved transmembrane segments. SK1 expression is restricted to the brain whereas SK2 and SK3 are more widely expressed. SK channels influence most excitable cells and participate in afterhyperpolarization (AHP) and spike-frequency adaptation. Human SK3 is a 731 amino acid protein that is expressed in muscles upon denervation, and it is a component of the presynaptic compartment in mature neuromuscμlar junctions. SK3 may also play a regμlatory role in synaptic transmission.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: hSK3, KCa2.3, Kcnn3, KCNN3_HUMAN, Potassium intermediate/small conductance calcium activated channel subfamily N member 3, SK3, SKCa 3, SKCa3, Small conductance calcium-activated potassium channel protein 3,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human KCNN3.

Dilution: WB 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: KCNN3 polyclonal antibody detects endogenous levels of KCNN3 protein.

Molecular Weight: ~ 82 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9UGI6

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only