Product Description

KCNN3 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS7920-50, BS7920-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9UGI6

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB 1:500 - 1:2000

Background: Small-conductance, calcium-activated K+ channels (SK channels) are activated in a voltage-independent manner, and they have a small unit conductance and high sensitivity to calcium. SK channels 1-3 contain intracellular N- and C- termini and 6 conserved transmembrane segments. SK1 expression is restricted to the brain whereas SK2 and SK3 are more widely expressed. SK channels influence most excitable cells and participate in afterhyperpolarization (AHP) and spike-frequency adaptation. Human SK3 is a 731 amino acid protein that is expressed in muscles upon denervation, and it is a component of the presynaptic compartment in mature neuromuscular junctions. SK3 may also play a regulatory role in synaptic transmission.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: KCNN3 polyclonal antibody detects endogenous levels of KCNN3 protein.

Bioworld Molecular Weight: ~ 82 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot (WB) analysis of KCNN3 polyclonal antibody

Alternative Name: hSK3;
KCa2.3;
Kcnn3;
KCNN3_HUMAN;
Potassium intermediate/small conductance calcium activated channel subfamily N member 3;
SK3;
SKCa 3;
SKCa3;
Small conductance calcium-activated potassium channel protein 3;

Immunogen: Recombinant full length Human KCNN3.

Conjugate: Unconjugated

Modification: Unmodified